Reactive Astrocytes in Neurodegenerative Diseases
نویسندگان
چکیده
منابع مشابه
Elusive roles for reactive astrocytes in neurodegenerative diseases
Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory response. They become reactive in response to virtually all pathological situations in the brain such as axotomy, ischemia, infection, and neurodegenerative diseases (ND). Astrocyte reactivity was originally characterized by morphological changes (hypertrophy, remodeling of processes) and the overexpression of ...
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INTRODUCTION Astrocytes have been considered mere supporting cells in the CNS. However, we now know that astrocytes are actively involved in many of the functions of the CNS and may play an important role in neurodegenerative diseases. DEVELOPMENT This article reviews the roles astrocytes play in CNS development and plasticity; control of synaptic transmission; regulation of blood flow, energ...
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ژورنال
عنوان ژورنال: Aging and disease
سال: 2019
ISSN: 2152-5250
DOI: 10.14336/ad.2018.0720